Dimethyl Sulfoxide 99.9% Pharma Grade 8 oz Bottle Hangzhou Yuzhou

Description

Product Overview

Dimethyl sulfoxide (DMSO) is a versatile aprotic solvent prized for its ability to dissolve a wide range of organic and inorganic compounds. Our offering provides 99.9% pharmaceutical‑grade purity, ensuring that the solvent behaves predictably in sensitive experiments and industrial processes. The product is supplied in an 8 oz (237 ml) amber glass bottle that shields the liquid from ultraviolet light, preserving its chemical integrity over time. The glass container also prevents leaching of plasticizers, a common concern with polymer vessels, and offers a robust barrier against accidental contamination. Each bottle is sealed with a tamper‑evident cap, guaranteeing that the solvent remains untouched from the moment of manufacture until it reaches your laboratory bench. The clear, colorless liquid exhibits a low odor profile, making it suitable for environments where scent control is important. Its high boiling point of 189 °C provides stability during prolonged heating cycles, while its freezing point of –18 °C allows for flexible storage options.

The DMSO is produced by Hangzhou Yuzhou Technology Co., Ltd., a manufacturer with a dedicated clean‑room facility that adheres to Good Manufacturing Practice (GMP) standards. Advanced distillation and recrystallization techniques are employed to remove trace impurities, delivering the advertised 99.9% purity level. Each batch undergoes rigorous analytical testing, including gas chromatography‑mass spectrometry (GC‑MS) and nuclear magnetic resonance (NMR) verification, to confirm the absence of residual solvents, heavy metals, and microbial contamination. Production records are maintained in a traceable digital system, allowing customers to request certificates of analysis (CoA) for any lot number. This systematic approach not only guarantees consistency across shipments but also supports regulatory compliance for pharmaceutical and research applications. The facility also implements a closed‑loop waste management protocol, ensuring that any by‑products are neutralized before disposal. Continuous environmental monitoring and periodic third‑party audits reinforce the commitment to both product excellence and sustainable manufacturing practices. Overall, the production pipeline is designed to minimize variability and maximize reliability for end‑users.

The physical dimensions of the container are compact, measuring 6.89 × 3.86 × 3.82 inches (17.5 × 9.8 × 9.7 cm) and weighing approximately 1.1 lb (0.5 kg) when filled. This size fits comfortably on standard laboratory shelves, fume hood benches, and mobile carts, allowing easy access during routine workflows. The amber glass is 0.5 mm thick, providing sufficient impact resistance while maintaining optical clarity for visual inspection of liquid level. The screw‑on cap incorporates a PTFE liner that creates a chemical‑resistant seal, preventing evaporation and ingress of moisture. A secondary safety label on the bottle indicates the hazard class, storage temperature range, and first‑aid measures, complying with OSHA and GHS labeling requirements. The bottle’s ergonomic design includes a recessed grip area, reducing the risk of slippage when handling the container with gloves. The transparent amber hue also allows technicians to quickly assess the remaining volume without opening the cap, supporting efficient inventory management in busy laboratory environments. All dimensions are listed on the product data sheet for precise integration into safety data documentation.

Dimethyl sulfoxide is classified as a hazardous material, requiring careful handling to avoid skin irritation and potential systemic effects. Users should wear appropriate personal protective equipment, including nitrile gloves, safety goggles, and lab coats, when transferring or dispensing the solvent. In case of accidental skin contact, the affected area should be flushed with copious amounts of water for at least 15 minutes, and medical attention sought if irritation persists. The product should be stored in a cool, well‑ventilated area away from direct sunlight, with the bottle sealed tightly to prevent moisture ingress. Although DMSO has a relatively low vapor pressure, it can penetrate certain plastics; therefore, it is recommended to keep the container away from incompatible materials such as polycarbonate and certain elastomers. The recommended storage temperature range is between 2 °C and 25 °C, ensuring the liquid remains stable and ready for use. Regularly inspect the cap and seal for signs of wear to maintain product integrity over its shelf life.

The 99.9% pharmaceutical‑grade DMSO complies with United States Pharmacopeia (USP) monograph specifications for purity, residual solvents, and microbial limits. It is also listed under the European Pharmacopoeia (Ph. Eur.) as a qualified solvent for medicinal product manufacturing. The product carries an ISO 9001:2015 certification for quality management, reflecting the manufacturer’s commitment to consistent process control and continuous improvement. Safety data sheets (SDS) are provided in full compliance with the Globally Harmonized System (GHS) and include detailed hazard classifications, first‑aid measures, and environmental impact information. Customers in regulated industries can request additional documentation, such as batch‑specific certificates of analysis, to support validation and audit requirements. By meeting these stringent standards, the solvent offers confidence for use in pharmaceutical research, clinical trials, and high‑purity analytical applications. The product is also free from chlorinated solvents, making it suitable for applications where trace halogen contamination must be avoided. Its low odor profile contributes to a safer working environment, reducing the need for extensive ventilation measures during routine handling.

Usage

In synthetic organic chemistry, DMSO serves as an excellent polar aprotic solvent for a variety of nucleophilic substitution and coupling reactions. Its high dielectric constant facilitates the dissolution of ionic reagents, while its ability to stabilize transition states accelerates reaction rates. Researchers often employ DMSO to dissolve poorly soluble substrates, such as heterocyclic compounds, before adding them to catalytic systems. The solvent’s broad temperature tolerance allows reactions to be conducted from –10 °C up to 150 °C without significant degradation, providing flexibility for both low‑temperature and high‑temperature protocols. When combined with reagents like lithium aluminum hydride or sodium borohydride, DMSO can act as a co‑solvent, enhancing the efficiency of reduction processes. The solvent’s low odor and minimal residue after evaporation simplify product isolation, allowing chemists to recover target compounds with high purity. Additionally, DMSO’s compatibility with a wide range of catalysts, including palladium and copper complexes, makes it a versatile choice for cross‑coupling and C‑H activation strategies.

DMSO is widely recognized as a cryoprotectant for biological samples, protecting cells from ice crystal formation during freezing. At concentrations of 5–10% v/v, it penetrates cell membranes and reduces osmotic stress, preserving viability of mammalian cells, stem cells, and tissue explants. Our high‑purity DMSO minimizes the introduction of toxic impurities that could compromise downstream assays, such as flow cytometry or cell culture proliferation studies. The amber glass packaging further safeguards the solvent from light‑induced degradation, which can generate reactive species detrimental to sensitive biomolecules. Users typically aliquot the solvent into sterile vials under a laminar flow hood, ensuring aseptic conditions. Proper thawing protocols, involving rapid warming in a 37 °C water bath, complement the protective effects of DMSO, resulting in high post‑thaw recovery rates. When combined with controlled‑rate freezers, DMSO enables the preservation of delicate cell lines for extended periods, supporting long‑term research projects and biobanking initiatives.

In industrial settings, DMSO is employed as a cleaning solvent for equipment that processes polymeric and electronic components. Its ability to dissolve a broad spectrum of organic residues, including oils, greases, and photoresist polymers, makes it valuable for maintaining high‑precision machinery. The low odor and non‑flammable nature of DMSO reduce occupational hazards compared with traditional chlorinated solvents. Operators can apply the solvent using spray systems or immersion baths, followed by a rinse with deionized water to remove any residual traces. Because DMSO does not react with most metals, it is safe for use on stainless‑steel and aluminum surfaces, extending the lifespan of costly production assets. Proper disposal follows local hazardous waste regulations, ensuring environmental compliance. The solvent’s high boiling point also allows for easy recovery through distillation, enabling recycling in closed‑loop cleaning systems and reducing overall chemical consumption. Routine monitoring of DMSO concentration in cleaning baths ensures consistent performance and helps schedule timely replenishment.

Analytical laboratories frequently use DMSO as a solvent for sample preparation in spectroscopy, chromatography, and mass spectrometry. Its high polarity and ability to solubilize a wide range of analytes, from small molecules to large biomolecules, facilitate the creation of homogeneous solutions required for accurate quantification. The low UV absorbance of DMSO minimizes background interference in UV‑Vis measurements, while its compatibility with reverse‑phase HPLC columns ensures sharp peak shapes and reproducible retention times. In nuclear magnetic resonance (NMR) spectroscopy, DMSO‑d6 is a common deuterated solvent; however, the non‑deuterated DMSO described here can serve as a cost‑effective alternative for routine assays where deuteration is not essential. Proper filtration of the solvent through 0.22 µm membranes before use eliminates particulate contaminants, preserving instrument integrity and extending the lifespan of sensitive analytical equipment. When preparing standards, DMSO’s stability over extended storage periods ensures that calibration curves remain reliable, reducing the need for frequent reagent replacement. Its miscibility with water and many organic solvents also allows for flexible formulation of mixed‑solvent systems tailored to specific analytical methods.

Why Choose Us

Hangzhou Yuzhou Technology Co., Ltd. has built a reputation for delivering high‑quality chemical products to laboratories worldwide. With over a decade of experience in solvent production, the company combines state‑of‑the‑art manufacturing facilities with a rigorous quality management system. Their commitment to continuous improvement is reflected in regular certifications, including ISO 9001 and ISO 14001, which demonstrate adherence to both product excellence and environmental responsibility. Customers benefit from a transparent supply chain, where each shipment is traceable back to its production batch, providing confidence in the consistency of the material. By partnering with a trusted supplier, researchers can focus on their scientific objectives rather than worrying about reagent variability. The company’s global distribution network ensures rapid delivery to major research hubs, minimizing downtime and supporting time‑critical projects. Their technical support team is available to assist with formulation advice, troubleshooting, and compliance documentation, reinforcing a partnership approach rather than a simple transaction.

Each batch of DMSO undergoes a comprehensive suite of analytical tests to verify its purity and performance characteristics. Gas chromatography‑mass spectrometry (GC‑MS) confirms the absence of residual solvents, while nuclear magnetic resonance (NMR) spectroscopy validates the molecular structure and detects any unexpected by‑products. Water content is measured using Karl Fischer titration, ensuring that moisture levels remain below 0.05%, a critical parameter for maintaining low odor and preventing hydrolysis of sensitive reagents. The final product is also subjected to a sterility check, guaranteeing that the solvent is free from microbial contamination. Detailed certificates of analysis (CoA) accompany every shipment, providing customers with the exact specifications and test results for their specific lot number. In addition, a subset of samples is sent to an independent third‑party laboratory for cross‑validation, reinforcing the reliability of the in‑house analytical data. This multilayered verification process gives users confidence that the solvent will perform consistently across a wide range of experimental conditions.

The amber glass bottle used for this DMSO product offers several practical advantages over plastic containers. Glass provides an impermeable barrier that prevents the ingress of atmospheric gases and moisture, which can degrade solvent quality over time. The amber tint blocks ultraviolet radiation, a known catalyst for photochemical reactions that could generate unwanted by‑products. Moreover, the thick‑walled design reduces the risk of breakage during handling and transport, while still being lightweight enough for easy maneuverability on laboratory benches. The screw‑cap with a PTFE liner ensures a tight seal, minimizing evaporation and preserving the low‑odor characteristic of the solvent. For added safety, the bottle is labeled with clear hazard symbols and storage instructions, complying with international standards such as GHS and OSHA. The transparent amber glass also allows users to visually monitor the remaining volume without opening the container, supporting efficient inventory control. Additionally, the glass material is chemically inert, eliminating the risk of leaching additives that could interfere with sensitive analytical procedures.

Beyond product quality, Hangzhou Yuzhou provides comprehensive after‑sales support to ensure a smooth experience for every customer. Their technical service team is reachable via email and phone during standard business hours, ready to answer formulation questions, suggest alternative solvents, or assist with troubleshooting unexpected results. For bulk orders, the company offers flexible shipping options, including express courier services and temperature‑controlled freight, to accommodate time‑sensitive projects. Customers can also access an online portal to track order status, download safety data sheets, and request additional documentation such as batch‑specific certificates of analysis. A dedicated warranty program covers any defects arising from manufacturing, reinforcing confidence in the durability and reliability of the amber glass packaging. The company also provides training webinars on best practices for solvent handling and storage, helping laboratories maintain safety standards and optimize their workflows. Feedback from users is actively collected and used to drive product improvements, ensuring that the DMSO continues to meet evolving scientific needs.

Key Features

• 99.9% pharmaceutical‑grade purity ensures reliable performance in sensitive research and production processes. It minimizes impurity‑related variability, delivering consistent results across batches.
• Amber glass bottle protects DMSO from UV light, preserving low odor and chemical stability over time. The sturdy construction also reduces risk of breakage during handling.
• Low odor formulation reduces scent impact in the lab, improving comfort during prolonged use. This feature is especially valuable in confined workspaces and shared environments.
• Wide temperature tolerance (‑18 °C to 189 °C) allows DMSO to be used in both cooling and heating applications. Enabling flexibility for cryopreservation and high‑temperature synthesis protocols.
• Dedicated customer support provides technical assistance, documentation, and warranty coverage for peace of mind. Responsive service helps resolve issues quickly, ensuring uninterrupted laboratory operations.

FAQ

What safety precautions should I take when handling DMSO?

Always wear nitrile gloves, safety goggles, and a lab coat when dispensing DMSO. Work in a well‑ventilated area or fume hood to avoid inhalation of vapors. If the solvent contacts skin, rinse the area with plenty of water for at least 15 minutes and seek medical advice if irritation persists.

Can I use this DMSO for cryopreservation of cells?

Yes, the 99.9% pure DMSO is suitable for cryoprotecting mammalian cells, stem cells, and tissue samples. Typical concentrations range from 5 to 10 % v/v, mixed with a compatible culture medium. Ensure the solvent is sterile and stored away from light to maintain its protective properties during freezing and thawing cycles.

How should I store DMSO to maintain its quality?

Store the amber glass bottle in a cool, dry place between 2 °C and 25 °C, away from direct sunlight and sources of heat. Keep the cap tightly sealed to prevent moisture ingress. For long‑term storage, avoid temperatures below –18 °C, as the solvent may solidify and require gentle warming to return to liquid form.

Is the DMSO compatible with common laboratory plastics?

DMSO can permeate certain plastics such as polycarbonate, polystyrene, and some elastomers, potentially causing swelling or leaching of additives. For best results, store and handle the solvent in glass containers or compatible polymers like PTFE and HDPE. Avoid prolonged contact with sensitive plastic components to preserve equipment integrity.